Mark Cruickshank
Mark Cruickshank
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Neonatal DNA methylation profile in human twins is specified by a complex interplay between intrauterine environmental and genetic factors, subject to tissue-specific influence
L Gordon, JE Joo, JE Powell, M Ollikainen, B Novakovic, X Li, ...
Genome research 22 (8), 1395-1406, 2012
Longitudinal, genome-scale analysis of DNA methylation in twins from birth to 18 months of age reveals rapid epigenetic change in early life and pair-specific effects of …
D Martino, YJ Loke, L Gordon, M Ollikainen, MN Cruickshank, R Saffery, ...
Genome biology 14 (5), 1-14, 2013
Analysis of epigenetic changes in survivors of preterm birth reveals the effect of gestational age and evidence for a long term legacy
MN Cruickshank, A Oshlack, C Theda, PG Davis, D Martino, P Sheehan, ...
Genome medicine 5 (10), 1-12, 2013
A critical assessment of the factors affecting reporter gene assays for promoter SNP function: a reassessment of− 308 TNF polymorphism function using a novel integrated …
M Karimi, LC Goldie, MN Cruickshank, EK Moses, LJ Abraham
European journal of human genetics 17 (11), 1454-1462, 2009
Tumor penetrating peptides inhibiting MYC as a potent targeted therapeutic strategy for triple-negative breast cancers
E Wang, A Sorolla, PT Cunningham, HM Bogdawa, S Beck, E Golden, ...
Oncogene 38 (1), 140-150, 2019
The impact of histone post-translational modifications on developmental gene regulation
MN Cruickshank, P Besant, D Ulgiati
Amino acids 39 (5), 1087-1105, 2010
The role of notch signaling in the development of a normal B‐cell repertoire
MN Cruickshank, D Ulgiati
Immunology and cell biology 88 (2), 117-124, 2010
Quantitative differences in chromatin accessibility across regulatory regions can be directly compared in distinct cell-types
M Cruickshank, E Fenwick, LJ Abraham, D Ulgiati
Biochemical and biophysical research communications 367 (2), 349-355, 2008
Human active X-specific DNA methylation events showing stability across time and tissues
JE Joo, B Novakovic, M Cruickshank, LW Doyle, JM Craig, R Saffery
European Journal of Human Genetics 22 (12), 1376-1381, 2014
Systematic chemical and molecular profiling of MLL-rearranged infant acute lymphoblastic leukemia reveals efficacy of romidepsin
MN Cruickshank, J Ford, LC Cheung, J Heng, S Singh, J Wells, TW Failes, ...
Leukemia 31 (1), 40-50, 2017
Promoter polymorphisms in two overlapping 6p25 genes implicate mitochondrial proteins in cognitive deficit in schizophrenia
A Jablensky, D Angelicheva, GJ Donohoe, M Cruickshank, DN Azmanov, ...
Molecular Psychiatry 17 (12), 1328-1339, 2012
Going back to the future with Guthrie-powered epigenome-wide association studies
MN Cruickshank, J Pitt, JM Craig
Genome medicine 4 (10), 1-4, 2012
Transcriptional effects of a lupus-associated polymorphism in the 5′ untranslated region (UTR) of human complement receptor 2 (CR2/CD21)
MN Cruickshank, M Karimi, RL Mason, E Fenwick, T Mercer, BP Tsao, ...
Molecular immunology 52 (3-4), 165-173, 2012
Cell-and stage-specific chromatin structure across the complement receptor 2 (CR2/CD21) promoter coincide with CBF1 and C/EBP-β binding in B cells
MN Cruickshank, E Fenwick, M Karimi, LJ Abraham, D Ulgiati
Molecular immunology 46 (13), 2613-2622, 2009
Acquired resistance during adoptive cell therapy by transcriptional silencing of immunogenic antigens
B Wylie, J Chee, CA Forbes, M Booth, SR Stone, A Buzzai, A Abad, ...
OncoImmunology 8 (8), 1609874, 2019
CD8+ XCR1neg dendritic cells express high levels of toll-like receptor 5 and a unique complement of endocytic receptors
B Wylie, J Read, AC Buzzai, T Wagner, N Troy, G Syn, SR Stone, B Foley, ...
Frontiers in immunology 9, 2990, 2019
Analysis of tandem E-box motifs within human Complement receptor 2 (CR2/CD21) promoter reveals cell specific roles for RP58, E2A, USF and localized chromatin accessibility
MN Cruickshank, J Dods, RL Taylor, M Karimi, EJ Fenwick, EA Quail, ...
The international journal of biochemistry & cell biology 64, 107-119, 2015
Impaired T cell proliferation by ex vivo BET-inhibition impedes adoptive immunotherapy in a murine melanoma model
J Chee, C Wilson, A Buzzai, B Wylie, CA Forbes, M Booth, N Principe, ...
Epigenetics 15 (1-2), 134-144, 2020
Focused transcription from the human CR2/CD21 core promoter is regulated by synergistic activity of TATA and Initiator elements in mature B cells
RL Taylor, MN Cruickshank, M Karimi, HL Ng, E Quail, KM Kaufman, ...
Cellular & molecular immunology 13 (1), 119-131, 2016
Romidepsin enhances the efficacy of cytarabine in vivo, revealing histone deacetylase inhibition as a promising therapeutic strategy for KMT2A-rearranged infant acute …
LC Cheung, MN Cruickshank, AM Hughes, S Singh, GA Chua, J Ford, ...
haematologica 104 (7), e300, 2019
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