Eriko Takano
Eriko Takano
Professor of Synthetic Biology, Manchester Institute of Biotechnology, University of Manchester
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antiSMASH 3.0—a comprehensive resource for the genome mining of biosynthetic gene clusters
T Weber, K Blin, S Duddela, D Krug, HU Kim, R Bruccoleri, SY Lee, ...
Nucleic acids research 43 (W1), W237-W243, 2015
antiSMASH: rapid identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genome sequences
MH Medema, K Blin, P Cimermancic, V De Jager, P Zakrzewski, ...
Nucleic acids research 39 (suppl_2), W339-W346, 2011
antiSMASH 4.0—improvements in chemistry prediction and gene cluster boundary identification
K Blin, T Wolf, MG Chevrette, X Lu, CJ Schwalen, SA Kautsar, ...
Nucleic acids research 45 (W1), W36-W41, 2017
antiSMASH 2.0—a versatile platform for genome mining of secondary metabolite producers
K Blin, MH Medema, D Kazempour, MA Fischbach, R Breitling, E Takano, ...
Nucleic acids research 41 (W1), W204-W212, 2013
Insights into secondary metabolism from a global analysis of prokaryotic biosynthetic gene clusters
P Cimermancic, MH Medema, J Claesen, K Kurita, LCW Brown, ...
Cell 158 (2), 412-421, 2014
Minimum information about a biosynthetic gene cluster
MH Medema, R Kottmann, P Yilmaz, M Cummings, JB Biggins, K Blin, ...
Nature chemical biology 11 (9), 625-631, 2015
γ-Butyrolactones: Streptomyces signalling molecules regulating antibiotic production and differentiation
E Takano
Current opinion in microbiology 9 (3), 287-294, 2006
A complex role for the γ‐butyrolactone SCB1 in regulating antibiotic production in Streptomyces coelicolor A3(2)
E Takano, R Chakraburtty, T Nihira, Y Yamada, MJ Bibb
Molecular microbiology 41 (5), 1015-1028, 2001
Detecting sequence homology at the gene cluster level with MultiGeneBlast
MH Medema, E Takano, R Breitling
Molecular biology and evolution 30 (5), 1218-1223, 2013
Transcriptional regulation of the redD transcriptional activator gene accounts for growth‐phase‐dependent production of the antibiotic undecylprodigiosin in Streptomyces …
E Takano, HC Gramajo, E Strauch, N Andres, J White, MJ Bibb
Molecular microbiology 6 (19), 2797-2804, 1992
Stationary‐phase production of the antibiotic actinorhodin in Streptomyces coelicolor A3(2) is transcriptionally regulated
HC Gramajo, E Takano, MJ Bibb
Molecular microbiology 7 (6), 837-845, 1993
The stringent response in Streptomyces coelicolor A3(2)
E Strauch, E Takano, HA Baylts, MJ Bibb
Molecular microbiology 5 (2), 289-298, 1991
Computational tools for the synthetic design of biochemical pathways
MH Medema, R Van Raaphorst, E Takano, R Breitling
Nature Reviews Microbiology 10 (3), 191-202, 2012
The sequence of a 1.8-Mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways
MH Medema, A Trefzer, A Kovalchuk, M van den Berg, U Müller, W Heijne, ...
Genome Biology and Evolution 2, 212-224, 2010
Purification and Structural Determination of SCB1, a γ-Butyrolactone That Elicits Antibiotic Production inStreptomyces coelicolor A3 (2)
E Takano, T Nihira, Y Hara, JJ Jones, CJL Gershater, Y Yamada, M Bibb
Journal of Biological Chemistry 275 (15), 11010-11016, 2000
Exploiting plug-and-play synthetic biology for drug discovery and production in microorganisms
MH Medema, R Breitling, R Bovenberg, E Takano
Nature Reviews Microbiology 9 (2), 131-137, 2011
A bacterial hormone (the SCB1) directly controls the expression of a pathway‐specific regulatory gene in the cryptic type I polyketide biosynthetic gene cluster of Streptomyces …
E Takano, H Kinoshita, V Mersinias, G Bucca, G Hotchkiss, T Nihira, ...
Molecular microbiology 56 (2), 465-479, 2005
The dynamic architecture of the metabolic switch in Streptomyces coelicolor
K Nieselt, F Battke, A Herbig, P Bruheim, A Wentzel, ŘM Jakobsen, ...
BMC genomics 11 (1), 10, 2010
The dynamic architecture of the metabolic switch in Streptomyces coelicolor
N Kay, B Florian, H Alexander, B Per, W Alexander, J Řyvind, S Hĺvard, ...
BMC Genomics 11, 2010
Deletion of a regulatory gene within the cpk gene cluster reveals novel antibacterial activity in Streptomyces coelicolor A3 (2)
M Gottelt, S Kol, JP Gomez-Escribano, M Bibb, E Takano
Microbiology 156 (8), 2343-2353, 2010
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