|PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients|
Y Nagata, KH Lan, X Zhou, M Tan, FJ Esteva, AA Sahin, KS Klos, P Li, ...
Cancer cell 6 (2), 117-127, 2004
|Mechanisms of disease: understanding resistance to HER2-targeted therapy in human breast cancer|
R Nahta, D Yu, MC Hung, GN Hortobagyi, FJ Esteva
Nature clinical practice Oncology 3 (5), 269-280, 2006
|Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth|
L Zhang, S Zhang, J Yao, FJ Lowery, Q Zhang, WC Huang, P Li, M Li, ...
Nature 527 (7576), 100-104, 2015
|p53 regulates epithelial–mesenchymal transition and stem cell properties through modulating miRNAs|
CJ Chang, CH Chao, W Xia, JY Yang, Y Xiong, CW Li, WH Yu, ...
Nature cell biology 13 (3), 317-323, 2011
|ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation|
JY Yang, CS Zong, W Xia, H Yamaguchi, Q Ding, X Xie, JY Lang, CC Lai, ...
Nature cell biology 10 (2), 138-148, 2008
|Upregulation of CXCR4 is essential for HER2-mediated tumor metastasis|
YM Li, Y Pan, Y Wei, X Cheng, BP Zhou, M Tan, X Zhou, W Xia, ...
Cancer cell 6 (5), 459-469, 2004
|Combating trastuzumab resistance by targeting SRC, a common node downstream of multiple resistance pathways|
S Zhang, WC Huang, P Li, H Guo, SB Poh, SW Brady, Y Xiong, LM Tseng, ...
Nature medicine 17 (4), 461-469, 2011
|Overexpression of ErbB2 in cancer and ErbB2-targeting strategies|
D Yu, MC Hung
Oncogene 19 (53), 6115-6121, 2000
|Overexpression of ErbB2 blocks Taxol-induced apoptosis by upregulation of p21Cip1, which inhibits p34Cdc2 kinase|
D Yu, T Jing, B Liu, J Yao, M Tan, TJ McDonnell, MC Hung
Molecular cell 2 (5), 581-591, 1998
|Activation of the Akt/mammalian target of rapamycin/4E-BP1 pathway by ErbB2 overexpression predicts tumor progression in breast cancers|
X Zhou, M Tan, VS Hawthorne, KS Klos, KH Lan, Y Yang, W Yang, ...
Clinical Cancer Research 10 (20), 6779-6788, 2004
|Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity|
CW Li, SO Lim, W Xia, HH Lee, LC Chan, CW Kuo, KH Khoo, SS Chang, ...
Nature communications 7 (1), 1-11, 2016
|Enhanced c-erbB-2/neu expression in human ovarian cancer cells correlates with more severe malignancy that can be suppressed by E1A|
D Yu, JK Wolf, M Scanlon, JE Price, MC Hung
Cancer research 53 (4), 891-898, 1993
|PTEN, PIK3CA, p-AKT, and p-p70S6K status: association with trastuzumab response and survival in patients with HER2-positive metastatic breast cancer|
FJ Esteva, H Guo, S Zhang, C Santa-Maria, S Stone, JS Lanchbury, ...
The American journal of pathology 177 (4), 1647-1656, 2010
|Overexpression of the c-erbB-2 gene enhanced intrinsic metastasis potential in human breast cancer cells without increasing their transformation abilities|
M Tan, J Yao, D Yu
Cancer research 57 (6), 1199-1205, 1997
|The Skp2-SCF E3 ligase regulates Akt ubiquitination, glycolysis, herceptin sensitivity, and tumorigenesis|
CH Chan, CF Li, WL Yang, Y Gao, SW Lee, Z Feng, HY Huang, KKC Tsai, ...
Cell 149 (5), 1098-1111, 2012
|Wild-type p53 suppresses angiogenesis in human leiomyosarcoma and synovial sarcoma by transcriptional suppression of vascular endothelial growth factor expression|
L Zhang, D Yu, M Hu, S Xiong, A Lang, LM Ellis, RE Pollock
Cancer research 60 (13), 3655-3661, 2000
|Fats and fatty oils|
A Thomas, B Matthäus, HJ Fiebig
Ullmann's Encyclopedia of Industrial Chemistry, 1-84, 2000
|c-erbB-2/neu overexpression enhances metastatic potential of human lung cancer cells by induction of metastasis-associated properties|
D Yu, SS Wang, KM Dulski, CM Tsai, GL Nicolson, MC Hung
Cancer research 54 (12), 3260-3266, 1994
|A robust assay for alternative lengthening of telomeres in tumors shows the significance of alternative lengthening of telomeres in sarcomas and astrocytomas|
JD Henson, JA Hannay, SW McCarthy, JA Royds, TR Yeager, ...
Clinical Cancer Research 11 (1), 217-225, 2005
|Deubiquitination and stabilization of PD-L1 by CSN5|
SO Lim, CW Li, W Xia, JH Cha, LC Chan, Y Wu, SS Chang, WC Lin, ...
Cancer cell 30 (6), 925-939, 2016