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Jeremy K Nicholson
Jeremy K Nicholson
Director, Australian National Phenome Center, Murdoch Univ. and Imperial College London
Geverifieerd e-mailadres voor murdoch.edu.au - Homepage
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'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data
JK Nicholson, JC Lindon, E Holmes
Xenobiotica 29 (11), 1181-1189, 1999
47071999
Host-gut microbiota metabolic interactions
JK Nicholson, E Holmes, J Kinross, R Burcelin, G Gibson, W Jia, ...
Science 336 (6086), 1262-1267, 2012
40772012
Metabonomics: a platform for studying drug toxicity and gene function
JK Nicholson, J Connelly, JC Lindon, E Holmes
Nature reviews Drug discovery 1 (2), 153-161, 2002
24912002
Metabolic profiling, metabolomic and metabonomic procedures for NMR spectroscopy of urine, plasma, serum and tissue extracts
O Beckonert, HC Keun, TMD Ebbels, J Bundy, E Holmes, JC Lindon, ...
Nature protocols 2 (11), 2692, 2007
21232007
Metabonomics
JK Nicholson, JC Lindon
Nature 455 (7216), 1054-1056, 2008
21092008
Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using 1H-NMR-based metabonomics
JT Brindle, H Antti, E Holmes, G Tranter, JK Nicholson, HWL Bethell, ...
Nature medicine 8 (12), 1439-1445, 2002
13782002
Understanding'global'systems biology: metabonomics and the continuum of metabolism
JK Nicholson, ID Wilson
Nature Reviews Drug Discovery 2 (8), 668-676, 2003
13432003
OPLS discriminant analysis: combining the strengths of PLS‐DA and SIMCA classification
M Bylesjö, M Rantalainen, O Cloarec, JK Nicholson, E Holmes, J Trygg
Journal of Chemometrics: A Journal of the Chemometrics Society 20 (8‐10 …, 2006
13362006
Symbiotic gut microbes modulate human metabolic phenotypes
M Li, B Wang, M Zhang, M Rantalainen, S Wang, H Zhou, Y Zhang, ...
Proceedings of the National Academy of Sciences 105 (6), 2117-2122, 2008
12312008
Metabolic profiling reveals a contribution of gut microbiota to fatty liver phenotype in insulin-resistant mice
ME Dumas, RH Barton, A Toye, O Cloarec, C Blancher, A Rothwell, ...
Proceedings of the national academy of sciences 103 (33), 12511-12516, 2006
11962006
750 MHz 1H and 1H-13C NMR spectroscopy of human blood plasma
JK Nicholson, PJD Foxall, M Spraul, RD Farrant, JC Lindon
Analytical chemistry 67 (5), 793-811, 1995
11711995
Human metabolic phenotype diversity and its association with diet and blood pressure
E Holmes, RL Loo, J Stamler, M Bictash, IKS Yap, Q Chan, T Ebbels, ...
Nature 453 (7193), 396-400, 2008
11482008
Gut microbiomes of Malawian twin pairs discordant for kwashiorkor
MI Smith, T Yatsunenko, MJ Manary, I Trehan, R Mkakosya, J Cheng, ...
Science 339 (6119), 548-554, 2013
11332013
Gut microorganisms, mammalian metabolism and personalized health care
JK Nicholson, E Holmes, ID Wilson
Nature Reviews Microbiology 3 (5), 431-438, 2005
11252005
Impact of the gut microbiota on inflammation, obesity, and metabolic disease
CL Boulangé, AL Neves, J Chilloux, JK Nicholson, ME Dumas
Genome medicine 8, 1-12, 2016
11212016
Pharmaco-metabonomic phenotyping and personalized drug treatment
T Andrew Clayton, JC Lindon, O Cloarec, H Antti, C Charuel, G Hanton, ...
Nature 440 (7087), 1073-1077, 2006
9982006
Statistical total correlation spectroscopy: an exploratory approach for latent biomarker identification from metabolic 1H NMR data sets
O Cloarec, ME Dumas, A Craig, RH Barton, J Trygg, J Hudson, ...
Analytical chemistry 77 (5), 1282-1289, 2005
9812005
Global metabolic profiling procedures for urine using UPLC–MS
EJ Want, ID Wilson, H Gika, G Theodoridis, RS Plumb, J Shockcor, ...
Nature protocols 5 (6), 1005-1018, 2010
9302010
Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism
TA Clayton, D Baker, JC Lindon, JR Everett, JK Nicholson
Proceedings of the National Academy of Sciences 106 (34), 14728-14733, 2009
8242009
Metabolic phenotyping in health and disease
E Holmes, ID Wilson, JK Nicholson
Cell 134 (5), 714-717, 2008
8242008
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Artikelen 1–20