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Mitchell K.P. Lai
Mitchell K.P. Lai
Memory, Aging and Cognition Ctr, National University of Singapore; University of Exeter, UK
Adresse e-mail validée de dementia-research.org - Page d'accueil
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Année
Ageing and the telomere connection: An intimate relationship with inflammation
J Zhang, G Rane, X Dai, MK Shanmugam, F Arfuso, RP Samy, MKP Lai, ...
Ageing Research Reviews 25, 55-69, 2016
3662016
Regional Multiple Pathology Scores Are Associated with Cognitive Decline in L ewy Body Dementias
DR Howlett, D Whitfield, M Johnson, J Attems, JT O'Brien, D Aarsland, ...
Brain Pathology 25 (4), 401-408, 2015
1982015
Reduced serotonin 5-HT1A receptor binding in the temporal cortex correlates with aggressive behavior in Alzheimer disease
MKP Lai, SWY Tsang, PT Francis, MM Esiri, J Keene, T Hope, ...
Brain Research 974 (1-2), 82-87, 2003
1862003
Psychosis of Alzheimer’s disease is associated with elevated muscarinic M2 binding in the cortex
MK P. Lai, OF Lai, J Keene, MM Esiri, PT Francis, T Hope, CPLH Chen
Neurology 57 (5), 805-811, 2001
1582001
Neurochemical basis for symptomatic treatment of Alzheimer's disease
PT Francis, MJ Ramírez, MK Lai
Neuropharmacology 59 (4-5), 221-229, 2010
1462010
Genome wide profiling of altered gene expression in the neocortex of Alzheimer's disease
MG Tan, WT Chua, MM Esiri, AD Smith, HV Vinters, MK Lai
Journal of Neuroscience Research 88 (6), 1157-1169, 2010
1302010
Extracellular vesicles are rapidly purified from human plasma by PRotein Organic Solvent PRecipitation (PROSPR)
X Gallart-Palau, A Serra, ASW Wong, S Sandin, MKP Lai, CP Chen, ...
Scientific Reports 5, 14664, 2015
1292015
Loss of serotonin 5-HT2A receptors in the postmortem temporal cortex correlates with rate of cognitive decline in Alzheimer’s disease
MK Lai, SW Tsang, JT Alder, J Keene, T Hope, MM Esiri, PT Francis, ...
Psychopharmacology 179 (3), 673-677, 2005
1242005
Impaired coupling of muscarinic M1 receptors to G-proteins in the neocortex is associated with severity of dementia in Alzheimer's disease
SWY Tsang, MKP Lai, S Kirvell, PT Francis, MM Esiri, T Hope, ...
Neurobiology of Aging 27 (9), 1216-1223, 2006
1172006
Involvement of the GABAergic system in depressive symptoms of Alzheimer's disease
M Garcia-Alloza, SW Tsang, FJ Gil-Bea, PT Francis, MK Lai, B Marcos, ...
Neurobiology of Aging 27 (8), 1110-1117, 2006
1042006
Postmortem serotoninergic correlates of cognitive decline in Alzheimer's disease
MKP Lai, SWY Tsang, PT Francis, J Keene, T Hope, MM Esiri, I Spence, ...
Neuroreport 13 (9), 1175-1178, 2002
1042002
Serotonergic therapies for cognitive symptoms in Alzheimer’s disease: rationale and current status
MJ Ramirez, MKP Lai, RM Tordera, PT Francis
Drugs 74 (7), 729-736, 2014
942014
The brain lipidomes of subcortical ischemic vascular dementia and mixed dementia
SM Lam, Y Wang, X Duan, MR Wenk, RN Kalaria, CP Chen, MKP Lai, ...
Neurobiology of Aging 35 (10), 2369-2381, 2014
912014
Pathophysiology of blood brain barrier dysfunction during chronic cerebral hypoperfusion in vascular cognitive impairment
V Rajeev, DY Fann, QN Dinh, HA Kim, TM De Silva, MKP Lai, CLH Chen, ...
Theranostics 12 (4), 1639, 2022
822022
F-box protein 7 mutations promote protein aggregation in mitochondria and inhibit mitophagy
ZD Zhou, SP Xie, S Sathiyamoorthy, WT Saw, TY Sing, SH Ng, HPH Chua, ...
Human Molecular Genetics 24 (22), 6314-6330, 2015
822015
AIM2 inflammasome mediates hallmark neuropathological alterations and cognitive impairment in a mouse model of vascular dementia
L Poh, DY Fann, P Wong, HM Lim, SL Foo, SW Kang, V Rajeev, ...
Molecular Psychiatry 26 (8), 4544-4560, 2021
802021
Andrographolide induces Nrf2 and heme oxygenase 1 in astrocytes by activating p38 MAPK and ERK
SY Wong, MGK Tan, PTH Wong, DR Herr, MKP Lai
Journal of Neuroinflammation 13 (1), 251, 2016
782016
Intact cannabinoid CB1 receptors in the Alzheimer's disease cortex
JH Lee, G Agacinski, JH Williams, GK Wilcock, MM Esiri, PT Francis, ...
Neurochemistry International 57 (8), 985-989, 2010
772010
Markers of cardiac dysfunction in cognitive impairment and dementia
S Hilal, YL Chai, MK Ikram, S Elangovan, TB Yeow, X Xin, JY Chong, ...
Medicine 94 (1), e297, 2015
762015
Selective loss of P2Y 2 nucleotide receptor immunoreactivity is associated with Alzheimer’s disease neuropathology
MKP Lai, MGK Tan, S Kirvell, C Hobbs, J Lee, MM Esiri, CP Chen, ...
Journal of Neural Transmission 115 (8), 1165-1172, 2008
652008
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