Anticancer kinase inhibitors impair intracellular viral trafficking and exert broad-spectrum antiviral effects E Bekerman, G Neveu, A Shulla, J Brannan, SY Pu, S Wang, F Xiao, ... The Journal of clinical investigation 127 (4), 1338-1352, 2017 | 230 | 2017 |
Single-cell transcriptional dynamics of flavivirus infection F Zanini, SY Pu, E Bekerman, S Einav, SR Quake Elife 7, e32942, 2018 | 148 | 2018 |
Successful propagation of flavivirus infectious cDNAs by a novel method to reduce the cryptic bacterial promoter activity of virus genomes SY Pu, RH Wu, CC Yang, TM Jao, MH Tsai, JC Wang, HM Lin, YS Chao, ... Journal of virology 85 (6), 2927-2941, 2011 | 117 | 2011 |
Feasibility and biological rationale of repurposing sunitinib and erlotinib for dengue treatment SY Pu, F Xiao, S Schor, E Bekerman, F Zanini, R Barouch-Bentov, ... Antiviral research 155, 67-75, 2018 | 98 | 2018 |
Synthesis and Structure–Activity Relationships of 3,5-Disubstituted-pyrrolo[2,3-b]pyridines as Inhibitors of Adaptor-Associated Kinase 1 with Antiviral Activity S Verdonck, SY Pu, FJ Sorrell, JM Elkins, M Froeyen, LJ Gao, LI Prugar, ... Journal of medicinal chemistry 62 (12), 5810-5831, 2019 | 53 | 2019 |
DNA methylation and genome rearrangement characteristics of phase change in cultured shoots of Sequoia sempervirens LC Huang, LJ Hsiao, SY Pu, CI Kuo, BL Huang, TC Tseng, HJ Huang, ... Physiologia plantarum 145 (2), 360-368, 2012 | 49 | 2012 |
MARCH8 ubiquitinates the hepatitis C virus nonstructural 2 protein and mediates viral envelopment S Kumar, R Barouch-Bentov, F Xiao, S Schor, S Pu, E Biquand, A Lu, ... Cell reports 26 (7), 1800-1814. e5, 2019 | 47 | 2019 |
Optimization of Isothiazolo[4,3-b]pyridine-Based Inhibitors of Cyclin G Associated Kinase (GAK) with Broad-Spectrum Antiviral Activity SY Pu, R Wouters, S Schor, J Rozenski, R Barouch-Bentov, LI Prugar, ... Journal of medicinal chemistry 61 (14), 6178-6192, 2018 | 40 | 2018 |
Interactions between the hepatitis C virus nonstructural 2 protein and host adaptor proteins 1 and 4 orchestrate virus release F Xiao, S Wang, R Barouch-Bentov, G Neveu, S Pu, M Beer, S Schor, ... MBio 9 (2), 10.1128/mbio. 02233-17, 2018 | 39 | 2018 |
Characterization of an efficient dengue virus replicon for development of assays of discovery of small molecules against dengue virus CC Yang, MH Tsai, HS Hu, SY Pu, RH Wu, SH Wu, HM Lin, JS Song, ... Antiviral research 98 (2), 228-241, 2013 | 34 | 2013 |
Potent antiviral activity of novel multi-substituted 4-anilinoquin (az) olines S Saul, SY Pu, WJ Zuercher, S Einav, CRM Asquith Bioorganic & Medicinal Chemistry Letters 30 (16), 127284, 2020 | 28 | 2020 |
A novel approach to propagate flavivirus infectious cDNA clones in bacteria by introducing tandem repeat sequences upstream of virus genome SY Pu, RH Wu, MH Tsai, CC Yang, CM Chang, A Yueh Journal of General Virology 95 (7), 1493-1503, 2014 | 28 | 2014 |
Resistance analysis and characterization of a thiazole analogue, BP008, as a potent hepatitis C virus NS5A inhibitor HM Lin, JC Wang, HS Hu, PS Wu, CC Yang, CP Wu, SY Pu, TA Hsu, ... Antimicrobial agents and chemotherapy 56 (1), 44-53, 2012 | 19 | 2012 |
Structure-activity relationship study of the pyridine moiety of isothiazolo [4, 3-b] pyridines as antiviral agents targeting cyclin G-associated kinase B Martinez-Gualda, SY Pu, M Froeyen, P Herdewijn, S Einav, ... Bioorganic & Medicinal Chemistry 28 (1), 115188, 2020 | 17 | 2020 |
Isothiazolo [4, 3-b] pyridines as inhibitors of cyclin G associated kinase: synthesis, structure–activity relationship studies and antiviral activity J Li, S Kovackova, S Pu, J Rozenski, S De Jonghe, S Einav, P Herdewijn Medchemcomm 6 (9), 1666-1672, 2015 | 17 | 2015 |
Phase-and age-related differences in protein tyrosine phosphorylation in Sequoia sempervirens LC Huang, SY Pu, T Murashige, SF Fu, TT Kuo, DD Huang, HJ Huang Biologia plantarum 47 (4), 601-603, 2003 | 17 | 2003 |
Cyclin G-associated kinase (GAK) affinity and antiviral activity studies of a series of 3-C-substituted isothiazolo [4, 3-b] pyridines R Wouters, SY Pu, M Froeyen, E Lescrinier, S Einav, P Herdewijn, ... European Journal of Medicinal Chemistry 163, 256-265, 2019 | 13 | 2019 |
BIKE regulates dengue virus infection and is a cellular target for broad-spectrum antivirals S Pu, S Schor, M Karim, S Saul, M Robinson, S Kumar, LI Prugar, ... Antiviral research 184, 104966, 2020 | 12 | 2020 |
The cargo adapter protein CLINT1 is phosphorylated by the Numb-associated kinase BIKE and mediates dengue virus infection S Schor, S Pu, V Nicolaescu, S Azari, M Kõivomägi, M Karim, ... Journal of Biological Chemistry 298 (6), 2022 | 4 | 2022 |
2565. A Novel Prognostic Gene Set for the Prediction of Severe Dengue ML Robinson, TE Sweeney, R Barouch-Bentov, MK Sahoo, AM Sanz, ... Open Forum Infectious Diseases 5 (suppl_1), S72-S72, 2018 | | 2018 |