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Hongjun Fu
Hongjun Fu
Geverifieerd e-mailadres voor osumc.edu
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Neuronal activity enhances tau propagation and tau pathology in vivo
JW Wu, SA Hussaini, IM Bastille, GA Rodriguez, A Mrejeru, K Rilett, ...
Nature neuroscience 19 (8), 1085-1092, 2016
6862016
Selective vulnerability in neurodegenerative diseases
H Fu, J Hardy, KE Duff
Nature neuroscience 21 (10), 1350-1358, 2018
4632018
scGNN is a novel graph neural network framework for single-cell RNA-Seq analyses
J Wang, A Ma, Y Chang, J Gong, Y Jiang, R Qi, C Wang, H Fu, Q Ma, ...
Nature communications 12 (1), 1882, 2021
3822021
Tau pathology induces excitatory neuron loss, grid cell dysfunction, and spatial memory deficits reminiscent of early Alzheimer’s disease
H Fu, GA Rodriguez, M Herman, S Emrani, E Nahmani, G Barrett, ...
Neuron 93 (3), 533-541. e5, 2017
2602017
Environmental novelty activates β2-adrenergic signaling to prevent the impairment of hippocampal LTP by Aβ oligomers
S Li, M Jin, D Zhang, T Yang, T Koeglsperger, H Fu, DJ Selkoe
Neuron 77 (5), 929-941, 2013
2062013
Complement component C3 and complement receptor type 3 contribute to the phagocytosis and clearance of fibrillar Aβ by microglia
H Fu, B Liu, JL Frost, S Hong, M Jin, B Ostaszewski, GM Shankar, ...
Glia, 2012
1832012
A tau homeostasis signature is linked with the cellular and regional vulnerability of excitatory neurons to tau pathology
H Fu, A Possenti, R Freer, Y Nakano, NC Hernandez Villegas, M Tang, ...
Nature neuroscience 22 (1), 47-56, 2019
1812019
Amyloid-β Immunotherapy for Alzheimer's Disease
HJ Fu, B Liu, JL Frost, CA Lemere
CNS & neurological disorders drug targets 9 (2), 197, 2010
1472010
Novel dimeric acetylcholinesterase inhibitor bis (7)-tacrine, but not donepezil, prevents glutamate-induced neuronal apoptosis by blocking N-methyl-D-aspartate receptors
W Li, R Pi, HHN Chan, H Fu, NTK Lee, HW Tsang, Y Pu, DC Chang, C Li, ...
Journal of Biological Chemistry 280 (18), 18179-18188, 2005
1422005
Bis (7)‐tacrine attenuates β amyloid‐induced neuronal apoptosis by regulating L‐type calcium channels
H Fu, W Li, Y Lao, J Luo, NTK Lee, KKW Kan, HW Tsang, KWK Tsim, ...
Journal of neurochemistry 98 (5), 1400-1410, 2006
1232006
A shared disease-associated oligodendrocyte signature among multiple CNS pathologies
M Kenigsbuch, P Bost, S Halevi, Y Chang, S Chen, Q Ma, R Hajbi, ...
Nature neuroscience 25 (7), 876-886, 2022
922022
Promising anti-Alzheimer’s dimer bis (7)-tacrine reduces β-amyloid generation by directly inhibiting BACE-1 activity
H Fu, W Li, J Luo, NTK Lee, M Li, KWK Tsim, Y Pang, MBH Youdim, ...
Biochemical and biophysical research communications 366 (3), 631-636, 2008
862008
scREAD: a single-cell RNA-Seq database for Alzheimer's disease
J Jiang, C Wang, R Qi, H Fu, Q Ma
Iscience 23 (11), 2020
772020
Aluminum-induced apoptosis in cultured cortical neurons and its effect on SAPK/JNK signal transduction pathway
HJ Fu, QS Hu, ZN Lin, TL Ren, H Song, CK Cai, SZ Dong
Brain research 980 (1), 11-23, 2003
752003
MER5101, a novel Aβ1-15: DT conjugate vaccine, generates a robust anti-Aβ antibody response and attenuates Aβ pathology and cognitive deficits in APPswe/PS1ΔE9 transgenic mice
B Liu, JL Frost, J Sun, H Fu, S Grimes, P Blackburn, CA Lemere
Journal of Neuroscience 33 (16), 7027-7037, 2013
682013
Synergistic neuroprotection by bis (7)-tacrine via concurrent blockade of N-methyl-D-aspartate receptors and neuronal nitric-oxide synthase
W Li, J Xue, C Niu, H Fu, CSC Lam, J Luo, HHN Chan, H Xue, KKW Kan, ...
Molecular pharmacology 71 (5), 1258-1267, 2007
642007
F‐box/LRR‐repeat protein 7 is genetically associated with Alzheimer's disease
G Tosto, H Fu, BN Vardarajan, JH Lee, R Cheng, D Reyes‐Dumeyer, ...
Annals of clinical and translational neurology 2 (8), 810-820, 2015
582015
Promising multifunctional anti-Alzheimer's dimer bis (7)-Cognitin acting as an activator of protein kinase C regulates activities of α-secretase and BACE-1 concurrently
H Fu, J Dou, W Li, W Cui, S Mak, Q Hu, J Luo, CSC Lam, Y Pang, ...
European journal of pharmacology 623 (1-3), 14-21, 2009
502009
Maternal low-level lead exposure reduces the expression of PSA-NCAM and the activity of sialyltransferase in the hippocampi of neonatal rat pups
Q Hu, H Fu, T Ren, S Wang, W Zhou, H Song, Y Han, S Dong
Neurotoxicology 29 (4), 675-681, 2008
472008
ANKRD16 prevents neuron loss caused by an editing-defective tRNA synthetase
MN Vo, M Terrey, JW Lee, B Roy, JJ Moresco, L Sun, H Fu, Q Liu, ...
Nature 557 (7706), 510-515, 2018
442018
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Artikelen 1–20