Carlos Bertoncini
Carlos Bertoncini
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Release of long-range tertiary interactions potentiates aggregation of natively unstructured α-synuclein
CW Bertoncini, YS Jung, CO Fernandez, W Hoyer, C Griesinger, TM Jovin, ...
Proceedings of the National Academy of Sciences 102 (5), 1430-1435, 2005
Direct observation of the interconversion of normal and toxic forms of α-synuclein
N Cremades, SIA Cohen, E Deas, AY Abramov, AY Chen, A Orte, ...
Cell 149 (5), 1048-1059, 2012
Structural characterization of copper (II) binding to α-synuclein: insights into the bioinorganic chemistry of Parkinson's disease
RM Rasia, CW Bertoncini, D Marsh, W Hoyer, D Cherny, M Zweckstetter, ...
Proceedings of the National Academy of Sciences 102 (12), 4294-4299, 2005
Interaction of α-synuclein with divalent metal ions reveals key differences: A link between structure, binding specificity and fibrillation enhancement
A Binolfi, RM Rasia, CW Bertoncini, M Ceolin, M Zweckstetter, ...
Journal of the American Chemical Society 128 (30), 9893-9901, 2006
Defining long-range order and local disorder in native α-synuclein using residual dipolar couplings
P Bernadó, CW Bertoncini, C Griesinger, M Zweckstetter, M Blackledge
Journal of the American Chemical Society 127 (51), 17968-17969, 2005
Familial mutants of α-synuclein with increased neurotoxicity have a destabilized conformation
CW Bertoncini, CO Fernandez, C Griesinger, TM Jovin, M Zweckstetter
Journal of Biological Chemistry 280 (35), 30649-30652, 2005
Site-specific interactions of Cu (II) with α and β-synuclein: Bridging the molecular gap between metal binding and aggregation
A Binolfi, GR Lamberto, R Duran, L Quintanar, CW Bertoncini, JM Souza, ...
Journal of the American Chemical Society 130 (35), 11801-11812, 2008
Fluorescence imaging of amyloid formation in living cells by a functional, tetracysteine-tagged α-synuclein
MJ Roberti, CW Bertoncini, R Klement, EA Jares-Erijman, TM Jovin
Nature methods 4 (4), 345-351, 2007
Protein amyloids develop an intrinsic fluorescence signature during aggregation
FTS Chan, GSK Schierle, JR Kumita, CW Bertoncini, CM Dobson, ...
Analyst 138 (7), 2156-2162, 2013
Peptide nanofibrils boost retroviral gene transfer and provide a rapid means for concentrating viruses
M Yolamanova, C Meier, AK Shaytan, V Vas, CW Bertoncini, F Arnold, ...
Nature nanotechnology 8 (2), 130-136, 2013
Bioinorganic chemistry of copper coordination to alpha-synuclein: relevance to Parkinson's disease
A Binolfi, L Quintanar, CW Bertoncini, C Griesinger, CO Fernández
Coordination Chemistry Reviews 256 (19-20), 2188-2201, 2012
Structural characterization of the intrinsically unfolded protein β-synuclein, a natural negative regulator of α-synuclein aggregation
CW Bertoncini, RM Rasia, GR Lamberto, A Binolfi, M Zweckstetter, ...
Journal of molecular biology 372 (3), 708-722, 2007
Targeting the intrinsically disordered structural ensemble of α-synuclein by small molecules as a potential therapeutic strategy for Parkinson’s disease
G Tóth, SJ Gardai, W Zago, CW Bertoncini, N Cremades, SL Roy, ...
PloS one 9 (2), e87133, 2014
Chaperone proteostasis in Parkinson's disease: Stabilization of the Hsp70/α‐synuclein complex by Hip
C Roodveldt, CW Bertoncini, A Andersson, AT Van Der Goot, ST Hsu, ...
The EMBO journal 28 (23), 3758-3770, 2009
On the mechanism of nonspecific inhibitors of protein aggregation: dissecting the interactions of α-synuclein with Congo red and lacmoid
C Lendel, CW Bertoncini, N Cremades, CA Waudby, M Vendruscolo, ...
Biochemistry 48 (35), 8322-8334, 2009
In situ measurements of the formation and morphology of intracellular β-amyloid fibrils by super-resolution fluorescence imaging
GS Kaminski Schierle, S van de Linde, M Erdelyi, EK Esbjörner, T Klein, ...
Journal of the American Chemical Society 133 (33), 12902-12905, 2011
Redox regulation of plant homeodomain transcription factors
AE Tron, CW Bertoncini, RL Chan, DH Gonzalez
Journal of Biological Chemistry 277 (38), 34800-34807, 2002
Direct observations of amyloid β self-assembly in live cells provide insights into differences in the kinetics of Aβ (1–40) and Aβ (1–42) aggregation
EK Esbjörner, F Chan, E Rees, M Erdelyi, LM Luheshi, CW Bertoncini, ...
Chemistry & biology 21 (6), 732-742, 2014
A FRET sensor for non-invasive imaging of amyloid formation in vivo
GSK Schierle, CW Bertoncini, FTS Chan, AT Van Der Goot, S Schwedler, ...
Chemphyschem: a European journal of chemical physics and physical chemistry …, 2011
Structural and mechanistic basis behind the inhibitory interaction of PcTS on α-synuclein amyloid fibril formation
GR Lamberto, A Binolfi, ML Orcellet, CW Bertoncini, M Zweckstetter, ...
Proceedings of the National Academy of Sciences 106 (50), 21057-21062, 2009
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