| Substrate-triggered formation and remarkable stability of the C− H bond-cleaving chloroferryl intermediate in the aliphatic halogenase, SyrB2 ML Matthews, CM Krest, EW Barr, FH Vaillancourt, CT Walsh, MT Green, ... Biochemistry 48 (20), 4331-4343, 2009 | 267 | 2009 |
| Elucidation of the Fe(iv)=O intermediate in the catalytic cycle of the halogenase SyrB2 SD Wong, M Srnec, ML Matthews, LV Liu, Y Kwak, K Park, CB Bell III, ... Nature 499 (7458), 320-323, 2013 | 251 | 2013 |
| Substrate positioning controls the partition between halogenation and hydroxylation in the aliphatic halogenase, SyrB2 ML Matthews, CS Neumann, LA Miles, TL Grove, SJ Booker, C Krebs, ... Proceedings of the National Academy of Sciences 106 (42), 17723-17728, 2009 | 239 | 2009 |
| Highly selective inhibitors of monoacylglycerol lipase bearing a reactive group that is bioisosteric with endocannabinoid substrates JW Chang, MJ Niphakis, KM Lum, AB Cognetta, C Wang, ML Matthews, ... Chemistry & biology 19 (5), 579-588, 2012 | 219 | 2012 |
| Spectroscopic Evidence for a High-Spin Br-Fe(IV)-Oxo Intermediate in the α-Ketoglutarate-Dependent Halogenase CytC3 from Streptomyces D Galonić Fujimori, EW Barr, ML Matthews, GM Koch, JR Yonce, ... Journal of the American Chemical Society 129 (44), 13408-13409, 2007 | 188 | 2007 |
| Direct nitration and azidation of aliphatic carbons by an iron-dependent halogenase ML Matthews, W Chang, AP Layne, LA Miles, C Krebs, JM Bollinger Jr Nature chemical biology 10 (3), 209-215, 2014 | 143 | 2014 |
| Enterococci enhance Clostridioides difficile pathogenesis AB Smith, ML Jenior, O Keenan, JL Hart, J Specker, A Abbas, PC Rangel, ... Nature 611 (7937), 780-786, 2022 | 107 | 2022 |
| Chemical proteomic profiling of human methyltransferases BD Horning, RM Suciu, DA Ghadiri, OA Ulanovskaya, ML Matthews, ... Journal of the American Chemical Society 138 (40), 13335-13343, 2016 | 101 | 2016 |
| Design of activated serine–containing catalytic triads with atomic-level accuracy S Rajagopalan, C Wang, K Yu, AP Kuzin, F Richter, S Lew, AE Miklos, ... Nature chemical biology 10 (5), 386-391, 2014 | 97 | 2014 |
| Electronic structure of the ferryl intermediate in the α-ketoglutarate dependent non-heme iron halogenase SyrB2: Contributions to H atom abstraction reactivity M Srnec, SD Wong, ML Matthews, C Krebs, JM Bollinger Jr, EI Solomon Journal of the American Chemical Society 138 (15), 5110-5122, 2016 | 93 | 2016 |
| Chemoproteomic profiling and discovery of protein electrophiles in human cells ML Matthews, L He, BD Horning, EJ Olson, BE Correia, JR Yates III, ... Nature chemistry 9 (3), 234-243, 2017 | 87 | 2017 |
| myo-Inositol oxygenase: a radical new pathway for O 2 and C–H activation at a nonheme diiron cluster JM Bollinger, Y Diao, ML Matthews, G Xing, C Krebs Dalton Transactions, 905-914, 2009 | 70 | 2009 |
| Metal-free class Ie ribonucleotide reductase from pathogens initiates catalysis with a tyrosine-derived dihydroxyphenylalanine radical EJ Blaesi, GM Palowitch, K Hu, AJ Kim, HR Rose, R Alapati, MG Lougee, ... Proceedings of the National Academy of Sciences 115 (40), 10022-10027, 2018 | 59 | 2018 |
| 2-Oxoglutarate-dependent oxygenases JM Bollinger Jr, W Chang, ML Matthews, RJ Martinie, AK Boal, C Krebs RSC Metallobiology. Royal Society of Chemistry, 2015 | 58 | 2015 |
| Mechanisms of 2-oxoglutarate-dependent oxygenases: The hydroxylation paradigm and beyond JM Bollinger Jr, W Chang, ML Matthews, RJ Martinie, AK Boal, C Krebs | 54 | 2015 |
| AurF from Streptomyces thioluteus and a Possible New Family of Manganese/Iron Oxygenases C Krebs, ML Matthews, W Jiang, JM Bollinger Biochemistry 46 (37), 10413-10418, 2007 | 47 | 2007 |
| A five-coordinate metal center in Co (II)-substituted VanX RM Breece, A Costello, B Bennett, TK Sigdel, ML Matthews, DL Tierney, ... Journal of Biological Chemistry 280 (12), 11074-11081, 2005 | 44 | 2005 |
| Evidence for modulation of oxygen rebound rate in control of outcome by iron (II)-and 2-oxoglutarate-dependent oxygenases J Pan, ES Wenger, ML Matthews, CJ Pollock, M Bhardwaj, AJ Kim, ... Journal of the American Chemical Society 141 (38), 15153-15165, 2019 | 40 | 2019 |
| The Nonribosomal Peptide Synthetase Enzyme DdaD Tethers Nβ-Fumaramoyl-l-2,3-diaminopropionate for Fe(II)/α-Ketoglutarate-Dependent Epoxidation by … MA Hollenhorst, SB Bumpus, ML Matthews, JM Bollinger Jr, NL Kelleher, ... Journal of the American Chemical Society 132 (44), 15773-15781, 2010 | 35 | 2010 |
| Design of benzoxathiazin-3-one 1, 1-dioxides as a new class of irreversible serine hydrolase inhibitors: discovery of a uniquely selective PNPLA4 inhibitor AF Kornahrens, AB Cognetta III, DM Brody, ML Matthews, BF Cravatt, ... Journal of the American Chemical Society 139 (20), 7052-7061, 2017 | 34 | 2017 |
Carsten KrebsPenn State UniversityVerified email at psu.edu
