Roger Larken Chang
Roger Larken Chang
Assistant Professor, Albert Einstein College of Medicine
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Genome‐scale models of metabolism and gene expression extend and refine growth phenotype prediction
EJ O'brien, JA Lerman, RL Chang, DR Hyduke, BØ Palsson
Molecular systems biology 9 (1), 693, 2013
Metabolic network reconstruction of Chlamydomonas offers insight into light‐driven algal metabolism
RL Chang, L Ghamsari, A Manichaikul, EFY Hom, S Balaji, W Fu, Y Shen, ...
Molecular systems biology 7 (1), 518, 2011
Network context and selection in the evolution to enzyme specificity
H Nam, NE Lewis, JA Lerman, DH Lee, RL Chang, D Kim, BO Palsson
Science 337 (6098), 1101-1104, 2012
Drug off-target effects predicted using structural analysis in the context of a metabolic network model
RL Chang, L Xie, L Xie, PE Bourne, BØ Palsson
PLoS Comput Biol 6 (9), e1000938, 2010
Modular organization of protein interaction networks
F Luo, Y Yang, CF Chen, R Chang, J Zhou, RH Scheuermann
Bioinformatics 23 (2), 207-214, 2007
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B Squires, C Macken, A Garcia-sastre, S Godbole, J Noronha, V Hunt, ...
Structural systems biology evaluation of metabolic thermotolerance in Escherichia coli
RL Chang, K Andrews, D Kim, Z Li, A Godzik, BO Palsson
Science 340 (6137), 1220-1223, 2013
Metabolic network analysis integrated with transcript verification for sequenced genomes
A Manichaikul, L Ghamsari, EFY Hom, C Lin, RR Murray, RL Chang, ...
Nature methods 6 (8), 589-592, 2009
BioHealthBase: informatics support in the elucidation of influenza virus host–pathogen interactions and virulence
B Squires, C Macken, A Garcia-Sastre, S Godbole, J Noronha, V Hunt, ...
Nucleic acids research 36 (suppl_1), D497-D503, 2008
Do genome‐scale models need exact solvers or clearer standards?
A Ebrahim, E Almaas, E Bauer, A Bordbar, AP Burgard, RL Chang, ...
Molecular systems biology 11 (10), 831, 2015
Systems biology of the structural proteome
E Brunk, N Mih, J Monk, Z Zhang, EJ O’Brien, SE Bliven, K Chen, ...
BMC systems biology 10 (1), 1-16, 2016
Transplantability of a circadian clock to a noncircadian organism
AH Chen, D Lubkowicz, V Yeong, RL Chang, PA Silver
Science advances 1 (5), e1500358, 2015
Characterizing posttranslational modifications in prokaryotic metabolism using a multiscale workflow
E Brunk, RL Chang, J Xia, H Hefzi, JT Yurkovich, D Kim, E Buckmiller, ...
Proceedings of the National Academy of Sciences 115 (43), 11096-11101, 2018
Protein structure, amino acid composition and sequence determine proteome vulnerability to oxidation-induced damage
RL Chang, JA Stanley, MC Robinson, JW Sher, Z Li, YA Chan, ...
EMBO J, 2020
Streptomyces thermoautotrophicus does not fix nitrogen
D MacKellar, L Lieber, JS Norman, A Bolger, C Tobin, JW Murray, ...
Scientific reports 6 (1), 1-12, 2016
Antibacterial mechanisms identified through structural systems pharmacology
RL Chang, L Xie, PE Bourne, BO Palsson
BMC systems biology 7 (1), 1-12, 2013
Natural and designed proteins inspired by extremotolerant organisms can form condensates and attenuate apoptosis in human cells
MT Veling, DT Nguyen, NN Thadani, ME Oster, NJ Rollins, KP Brock, ...
ACS Synthetic Biology 11 (3), 1292-1302, 2022
Multi-omics Analysis of Dsup Expressing Human Cells Reveals Open Chromatin Architectural Dynamics Underyling Radioprotection
C Westover, D Najjar, C Meydan, K Grigorev, MT Veling, RL Chang, ...
BioRxiv, 2020.11. 10.373571, 2022
Systems level analysis of the Chlamydomonas reinhardtii metabolic network reveals variability in evolutionary co-conservation
A Chaiboonchoe, L Ghamsari, B Dohai, P Ng, B Khraiwesh, A Jaiswal, ...
Molecular BioSystems 12 (8), 2394-2407, 2016
Deterministic graph-theoretic algorithm for detecting modules in biological interaction networks
RL Chang, F Luo, S Johnson, RH Scheuermann
International journal of bioinformatics research and applications 6 (2), 101, 2010
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