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Abdul Basit
Abdul Basit
Associate Director, Large molecule, Discovery Bioanalysis, Charles River Laboratories
Geverifieerd e-mailadres voor crl.com
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Age‐and genotype‐dependent variability in the protein abundance and activity of six major uridine diphosphate‐glucuronosyltransferases in human liver
DK Bhatt, A Mehrotra, A Gaedigk, R Chapa, A Basit, H Zhang, ...
Clinical Pharmacology & Therapeutics 105 (1), 131-141, 2019
1032019
Starch-based bio-elastomers functionalized with red beetroot natural antioxidant
TN Tran, A Athanassiou, A Basit, IS Bayer
Food Chemistry 216, 324-333, 2017
952017
Acid ceramidase in melanoma expression, localization, and effects of pharmacological inhibition
N Realini, F Palese, D Pizzirani, S Pontis, A Basit, A Bach, A Ganesan, ...
Journal of Biological Chemistry 291 (5), 2422-2434, 2016
842016
Defective Sphingosine-1-phosphate metabolism is a druggable target in Huntington’s disease
Scientific Reports 7, 2017
752017
Kidney cortical transporter expression across species using quantitative proteomics
A Basit, Z Radi, VS Vaidya, M Karasu, B Prasad
Drug Metabolism and Disposition 47 (8), 802-808, 2019
702019
Characterization of Differential Tissue Abundance of Major Non-CYP Enzymes in Human
A Basit, NK Neradugomma, C Wolford, PW Fan, B Murray, RH Takahashi, ...
Molecular Pharmaceutics 17 (11), 4114-4124, 2020
612020
Hepatic abundance and activity of androgen-and drug-metabolizing enzyme UGT2B17 are associated with genotype, age, and sex
DK Bhatt, A Basit, H Zhang, A Gaedigk, S Lee, KG Claw, A Mehrotra, ...
Drug Metabolism and Disposition 46 (6), 888-896, 2018
542018
Rapid evaluation of 25 key sphingolipids and phosphosphingolipids in human plasma by lc-ms/ms
A Basit, D Piomelli, A Armirotti
Analytical and bioanalytical chemistry 407 (17), 5189-5198, 2015
532015
Methamphetamine accelerates cellular senescence through stimulation of de novo ceramide biosynthesis
G Astarita, A Avanesian, B Grimaldi, N Realini, Z Justinova, LV Panlilio, ...
PloS one 10 (2), e0116961, 2015
512015
Major glucuronide metabolites of testosterone are primarily transported by MRP2 and MRP3 in human liver, intestine and kidney
CY Li, A Basit, A Gupta, Z Gáborik, E Kis, B Prasad
The Journal of steroid biochemistry and molecular biology 191, 105350, 2019
502019
De novo synthesis of sphingolipids is defective in experimental models of Huntington's Disease
A Di Pardo, A Basit, A Armirotti, E Amico, S Castaldo, G Pepe, F Marracino, ...
Frontiers in neuroscience 11, 698, 2017
492017
Sample preparation and orthogonal chromatography for broad polarity range plasma metabolomics: Application to human subjects with neurodegenerative dementia
A Armirotti, A Basit, N Realini, C Caltagirone, P Bossù, G Spalletta, ...
Analytical biochemistry 455, 48-54, 2014
482014
Elevated plasma ceramide levels in post-menopausal women: a cross-sectional study
V Vozella, A Basit, F Piras, N Realini, A Armirotti, P Bossù, F Assogna, ...
Aging (Albany NY) 11 (1), 73, 2019
442019
Quantitative characterization of UDP-glucuronosyltransferase 2B17 in human liver and intestine and its role in testosterone first-pass metabolism
H Zhang, A Basit, D Busch, K Yabut, DK Bhatt, M Drozdzik, M Ostrowski, ...
Biochemical pharmacology 156, 32-42, 2018
422018
Ion mobility mass spectrometry enhances low-abundance species detection in untargeted lipidomics
A Basit, S Pontis, D Piomelli, A Armirotti
Metabolomics 12 (3), 50, 2016
412016
Peroxide-dependent MGL sulfenylation regulates 2-AG-mediated endocannabinoid signaling in brain neurons
EY Dotsey, KM Jung, A Basit, D Wei, J Daglian, F Vacondio, A Armirotti, ...
Chemistry & biology 22 (5), 619-628, 2015
402015
Age-dependent changes in nervonic acid-containing sphingolipids in mouse hippocampus
V Vozella, A Basit, A Misto, D Piomelli
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2017
382017
Optimized renal transporter quantification by using aquaporin 1 and aquaporin 2 as anatomical markers: application in characterizing the ontogeny of renal transporters and its …
CY Li, C Hosey-Cojocari, A Basit, JD Unadkat, JS Leeder, B Prasad
The AAPS journal 21 (5), 1-8, 2019
372019
Quantitative Investigation of Irinotecan Metabolism, Transport, and Gut Microbiome Activation
MM Parvez, A Basit, PB Jariwala, Z Gáborik, E Kis, S Heyward, ...
Drug Metabolism and Disposition 49 (8), 683-693, 2021
352021
Sphingomyelin as a myelin biomarker in CSF of acquired demyelinating neuropathies
G Capodivento, D Visigalli, M Garnero, R Fancellu, MD Ferrara, A Basit, ...
Scientific reports 7 (1), 1-9, 2017
332017
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Artikelen 1–20