Maulik N Thaker
Maulik N Thaker
Novartis Institutes for Biomedical Research
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The comprehensive antibiotic resistance database
AG McArthur, N Waglechner, F Nizam, A Yan, MA Azad, AJ Baylay, ...
Antimicrobial agents and chemotherapy 57 (7), 3348-3357, 2013
The tetracycline resistome
M Thaker, P Spanogiannopoulos, GD Wright
Cellular and Molecular Life Sciences 67, 419-431, 2010
Identifying producers of antibacterial compounds by screening for antibiotic resistance
MN Thaker, W Wang, P Spanogiannopoulos, N Waglechner, AM King, ...
Nature biotechnology 31 (10), 922-927, 2013
Glycopeptide antibiotic biosynthesis
G Yim, MN Thaker, K Koteva, G Wright
The Journal of antibiotics 67 (1), 31-41, 2014
Induction of antimicrobial activities in heterologous streptomycetes using alleles of the Streptomyces coelicolor gene absA1
NL McKenzie, M Thaker, K Koteva, DW Hughes, GD Wright, JR Nodwell
The Journal of antibiotics 63 (4), 177-182, 2010
A cryptic polyene biosynthetic gene cluster in Streptomyces calvus is expressed upon complementation with a functional bldA gene
L Kalan, A Gessner, MN Thaker, N Waglechner, XM Zhu, A Szawiola, ...
Chemistry & biology 20 (10), 1214-1224, 2013
Characterization of a rifampin-inactivating glycosyltransferase from a screen of environmental actinomycetes
P Spanogiannopoulos, M Thaker, K Koteva, N Waglechner, GD Wright
Antimicrobial agents and chemotherapy 56 (10), 5061-5069, 2012
Opportunities for synthetic biology in antibiotics: expanding glycopeptide chemical diversity
MN Thaker, GD Wright
ACS synthetic biology 4 (3), 195-206, 2015
Vancomycin-variable enterococci can give rise to constitutive resistance during antibiotic therapy
MN Thaker, L Kalan, N Waglechner, A Eshaghi, SN Patel, S Poutanen, ...
Antimicrobial agents and chemotherapy 59 (3), 1405-1410, 2015
Biosynthesis of the Fluorinated Natural Product Nucleocidin in Streptomyces calvus Is Dependent on the bldA‐Specified Leu‐tRNAUUA Molecule
XM Zhu, S Hackl, MN Thaker, L Kalan, C Weber, DS Urgast, EM Krupp, ...
ChemBioChem 16 (17), 2498-2506, 2015
Antibiotic resistance–mediated isolation of scaffold-specific natural product producers
MN Thaker, N Waglechner, GD Wright
nature protocols 9 (6), 1469-1479, 2014
How to make a glycopeptide: a synthetic biology approach to expand antibiotic chemical diversity
G Yim, W Wang, MN Thaker, S Tan, GD Wright
ACS Infectious Diseases 2 (9), 642-650, 2016
Harnessing the Synthetic Capabilities of Glycopeptide Antibiotic Tailoring Enzymes: Characterization of the UK‐68,597 Biosynthetic Cluster
G Yim, L Kalan, K Koteva, MN Thaker, N Waglechner, I Tang, GD Wright
ChemBioChem 15 (17), 2613-2623, 2014
Glycopeptide sulfation evades resistance
L Kalan, J Perry, K Koteva, M Thaker, G Wright
Journal of bacteriology 195 (1), 167-171, 2013
Increased growth of micropropagated banana (Musa paradisiaca) with VAM symbiont
MN Thaker, YT Jasrai
Plant Tissue Cult 12 (2), 147-154, 2002
Biosynthetic gene cluster and antimicrobial activity of the elfamycin antibiotic factumycin
MN Thaker, M García, K Koteva, N Waglechner, D Sorensen, R Medina, ...
Medchemcomm 3 (8), 1020-1026, 2012
Resistance-guided discovery of elfamycin antibiotic producers with antigonococcal activity
V Yarlagadda, R Medina, TA Johnson, KP Koteva, G Cox, MN Thaker, ...
ACS Infectious Diseases 6 (12), 3163-3173, 2020
Split chloramphenicol acetyl-transferase assay reveals self-ubiquitylation-dependent regulation of UBE3B
O Levin-Kravets, A Kordonsky, A Shusterman, S Biswas, A Persaud, ...
Journal of molecular biology 433 (23), 167276, 2021
Allosteric Inhibition Restricts Motion of the SMURF1 Glycine Hinge and Reverses Experimental Pulmonary Arterial Hypertension
AM Rothman, A Florentin, C Quigley, F Zink, O Bonneau, R Hemming, ...
Circulation 148 (Suppl_1), A14275-A14275, 2023
Nucleotide Sequencing & Functional Analysis of Some Genes in PKS Cluster of S. flaviscleroticus and Studies on Mode of Action of the Polyketide
M Thaker
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