| Heart disease and stroke statistics—2016 update: a report from the American Heart Association D Mozaffarian, EJ Benjamin, AS Go, DK Arnett, MJ Blaha, M Cushman, ... circulation 133 (4), e38-e360, 2016 | 72848* | 2016 |
| Heart disease and stroke statistics 2005 update American Heart Association http://www. americanheart. org/statistics/, 2005 | 8560* | 2005 |
| Genetic studies of body mass index yield new insights for obesity biology AE Locke, B Kahali, SI Berndt, AE Justice, TH Pers, FR Day, C Powell, ... Nature 518 (7538), 197-206, 2015 | 4619 | 2015 |
| Biological, clinical and population relevance of 95 loci for blood lipids TM Teslovich, K Musunuru, AV Smith, AC Edmondson, IM Stylianou, ... Nature 466 (7307), 707-713, 2010 | 4026 | 2010 |
| Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index EK Speliotes, CJ Willer, SI Berndt, KL Monda, G Thorleifsson, AU Jackson, ... Nature genetics 42 (11), 937-948, 2010 | 3517 | 2010 |
| Albuminuria and risk of cardiovascular events, death, and heart failure in diabetic and nondiabetic individuals HC Gerstein, JFE Mann, Q Yi, B Zinman, SF Dinneen, B Hoogwerf, ... Jama 286 (4), 421-426, 2001 | 3266 | 2001 |
| Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study BF Voight, GM Peloso, M Orho-Melander, R Frikke-Schmidt, M Barbalic, ... The Lancet 380 (9841), 572-580, 2012 | 2527 | 2012 |
| Genomewide association analysis of coronary artery disease NJ Samani, J Erdmann, AS Hall, C Hengstenberg, M Mangino, B Mayer, ... New England Journal of Medicine 357 (5), 443-453, 2007 | 2460 | 2007 |
| A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease Nature genetics 47 (10), 1121-1130, 2015 | 2336 | 2015 |
| Long-term ACE-inhibitor therapy in patients with heart failure or left-ventricular dysfunction: a systematic overview of data from individual patients MD Flather, S Yusuf, L Køber, M Pfeffer, A Hall, G Murray, ... The Lancet 355 (9215), 1575-1581, 2000 | 2301 | 2000 |
| Hundreds of variants clustered in genomic loci and biological pathways affect human height H Lango Allen, K Estrada, G Lettre, SI Berndt, MN Weedon, F Rivadeneira, ... Nature 467 (7317), 832-838, 2010 | 2297 | 2010 |
| Effect of rosiglitazone on the frequency of diabetes in patients with impaired glucose tolerance or impaired fasting glucose: a randomised controlled trial DREAM (Diabetes REduction Assessment with ramipril and rosiglitazone ... The Lancet 368 (9541), 1096-1105, 2006 | 2229 | 2006 |
| Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease H Schunkert, IR König, S Kathiresan, MP Reilly, TL Assimes, H Holm, ... Nature genetics 43 (4), 333-338, 2011 | 2187 | 2011 |
| Defining the role of common variation in the genomic and biological architecture of adult human height AR Wood, T Esko, J Yang, S Vedantam, TH Pers, S Gustafsson, AY Chu, ... Nature genetics 46 (11), 1173-1186, 2014 | 2070 | 2014 |
| Six new loci associated with body mass index highlight a neuronal influence on body weight regulation Nature genetics 41 (1), 25-34, 2009 | 2057 | 2009 |
| Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial RECOVERY Collaborative Group Lancet (London, England) 397 (10285), 1637, 2021 | 1838* | 2021 |
| Large-scale association analysis identifies new risk loci for coronary artery disease CARDIoGRAMplusC4D Consortium, P Deloukas, S Kanoni, C Willenborg, ... Nature genetics 45 (1), 25-33, 2013 | 1726 | 2013 |
| Common variants near MC4R are associated with fat mass, weight and risk of obesity RJF Loos, CM Lindgren, S Li, E Wheeler, JH Zhao, I Prokopenko, ... Nature genetics 40 (6), 768-775, 2008 | 1564 | 2008 |
| Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants 1958 Birth Cohort Controls: Jones Richard W 18 McArdle Wendy L 18 Ring Susan ... Nature genetics 39 (11), 1329-1337, 2007 | 1423 | 2007 |
| Effect of ramipril on mortality and morbidity of survivors of acute myocardial infarction with clinical evidence of heart failure AIRE Study Investigators Lancet 342, 821-828, 1993 | 1372 | 1993 |
