| The small molecule IMR-1 inhibits the notch transcriptional activation complex to suppress tumorigenesis L Astudillo, TG Da Silva, Z Wang, X Han, K Jin, J VanWye, X Zhu, ... Cancer research 76 (12), 3593-3603, 2016 | 71 | 2016 |
| Quantitative study of protein–protein interactions by quartz nanopipettes PB Tiwari, L Astudillo, J Miksovska, X Wang, W Li, Y Darici, J He Nanoscale 6 (17), 10255-10263, 2014 | 36 | 2014 |
| Reduction of the internal disulfide bond between Cys 38 and 83 switches the ligand migration pathway in cytoglobin L Astudillo, S Bernad, V Derrien, P Sebban, J Miksovska Journal of inorganic biochemistry 129, 23-29, 2013 | 35 | 2013 |
| Differential abundance of CK1α provides selectivity for pharmacological CK1α activators to target WNT-dependent tumors B Li, D Orton, LR Neitzel, L Astudillo, C Shen, J Long, X Chen, ... Science signaling 10 (485), eaak9916, 2017 | 33 | 2017 |
| Probing the role of the internal disulfide bond in regulating conformational dynamics in neuroglobin L Astudillo, S Bernad, V Derrien, P Sebban, J Miksovska Biophysical journal 99 (2), L16-L18, 2010 | 30 | 2010 |
| Characterization of molecular mechanism of neuroglobin binding to cytochrome c: A surface plasmon resonance and isothermal titration calorimetry study PB Tiwari, L Astudillo, K Pham, X Wang, J He, S Bernad, V Derrien, ... Inorganic Chemistry Communications 62, 37-41, 2015 | 20 | 2015 |
| Pharmacological disruption of the Notch1 transcriptional complex inhibits tumor growth by selectively targeting cancer stem cells A Alvarez-Trotta, W Guerrant, L Astudillo, M Lahiry, G Diluvio, E Shersher, ... Cancer research 81 (12), 3347-3357, 2021 | 19 | 2021 |
| Conformational dynamics in human neuroglobin: effect of His64, Val68, and Cys120 on ligand migration L Astudillo, S Bernad, V Derrien, P Sebban, J Miksovska Biochemistry 51 (50), 9984-9994, 2012 | 18 | 2012 |
| Notch represses transcription by PRC2 recruitment to the ternary complex X Han, P Ranganathan, C Tzimas, KL Weaver, K Jin, L Astudillo, W Zhou, ... Molecular Cancer Research 15 (9), 1173-1183, 2017 | 17 | 2017 |
| The CK1α Activator Pyrvinium Enhances the Catalytic Efficiency (kcat/Km) of CK1α C Shen, B Li, L Astudillo, MP Deutscher, MH Cobb, AJ Capobianco, E Lee, ... Biochemistry 58 (51), 5102-5106, 2019 | 13 | 2019 |
| Latino academic resilience: Stories of high achieving middle school ELLs and the teachers and families that help them succeed M Astudillo University of Rhode Island, 2015 | 3 | 2015 |
| Conformational Dynamics Associated with Ligand Binding to Vertebrate Hexa-coordinate Hemoglobins L Astudillo | 3 | 2014 |
| A novel chemical attack on Notch-mediated transcription by targeting the NACK ATPase G Diluvio, TT Kelley, M Lahiry, A Alvarez-Trotta, EM Kolb, E Shersher, ... Molecular Therapy-Oncolytics 28, 307-320, 2023 | 1 | 2023 |
| Cytoglobin Interactions with Hydrophobic Probe 1, 8-ANS L Astudillo, K Pham, S Bernad, V Derrien, P Sebban, J Miksovska Biophysical Journal 104 (2), 563a, 2013 | 1 | 2013 |
| Time Resolved Thermodynamics Associated with Diatomic Ligand Dissociation from Globins J Miksovska, L Astudillo Thermodynamics-Interaction Studies-Solids, Liquids and Gases, 2011 | 1 | 2011 |
| Improved inhibitors of the notch transcriptional activation complex and methods for use of the same AJ Capobianco, M Spyvee, L Astudillo, D Orton US Patent App. 17/602,311, 2022 | | 2022 |
| Identification of small molecule inhibitors of the notch transcriptional activation complex L Astudillo, A Capobianco Cancer Research 77 (13_Supplement), 196-196, 2017 | | 2017 |
| Abstract A39: A small molecule inhibitor of the Notch transcriptional activation complex L Astudillo, AJ Capobianco Clinical Cancer Research 23 (1_Supplement), A39-A39, 2017 | | 2017 |
| Abstract A33: Discovery of novel anti-cancer therapeutic agents for Notch activation complex kinase (NACK) targeting the Notch pathway X Zhu, Z Wang, K Jin, L Astudillo, W Zhou, J Chen, P Buchwald, ... Clinical Cancer Research 23 (1_Supplement), A33-A33, 2017 | | 2017 |
| Gas-phase, conformational dynamics hexa-coordinated globin proteins E Schenk, R Almeida, L Astudillo, J Miksovska, M Ridgeway, M Park, ... EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS 42, S70-S70, 2013 | | 2013 |
