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Manuela Baccarini
Manuela Baccarini
Professor of Cell Signaling, University of Vienna
Geverifieerd e-mailadres voor univie.ac.at
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RASSF1A elicits apoptosis through an MST2 pathway directing proapoptotic transcription by the p73 tumor suppressor protein
D Matallanas, D Romano, K Yee, K Meissl, L Kucerova, D Piazzolla, ...
Molecular cell 27 (6), 962-975, 2007
4462007
Central role for type I interferons and Tyk2 in lipopolysaccharide-induced endotoxin shock
M Karaghiosoff, R Steinborn, P Kovarik, G Kriegshäuser, M Baccarini, ...
Nature immunology 4 (5), 471-477, 2003
4412003
Embryonic lethality and fetal liver apoptosis in mice lacking the c‐raf‐1 gene
M Mikula, M Schreiber, Z Husak, L Kucerova, J Rüth, R Wieser, ...
The EMBO journal, 2001
4072001
Selective requirement of PI3K/PDK1 signaling for Kras oncogene-driven pancreatic cell plasticity and cancer
S Eser, N Reiff, M Messer, B Seidler, K Gottschalk, M Dobler, M Hieber, ...
Cancer cell 23 (3), 406-420, 2013
3892013
Role of the kinase MST2 in suppression of apoptosis by the proto-oncogene product Raf-1
E O'Neill, L Rushworth, M Baccarini, W Kolch
Science 306 (5705), 2267-2270, 2004
3682004
Raf kinases in cancer–roles and therapeutic opportunities
G Maurer, B Tarkowski, M Baccarini
Oncogene 30 (32), 3477-3488, 2011
3482011
c-Raf, but not B-Raf, is essential for development of K-Ras oncogene-driven non-small cell lung carcinoma
RB Blasco, S Francoz, D Santamaría, M Canamero, P Dubus, J Charron, ...
Cancer cell 19 (5), 652-663, 2011
3322011
Raf-1-associated protein phosphatase 2A as a positive regulator of kinase activation
D Abraham, K Podar, M Pacher, M Kubicek, N Welzel, BA Hemmings, ...
Journal of Biological Chemistry 275 (29), 22300-22304, 2000
3062000
Raf-1 regulates Rho signaling and cell migration
K Ehrenreiter, D Piazzolla, V Velamoor, I Sobczak, JV Small, J Takeda, ...
The Journal of cell biology 168 (6), 955-964, 2005
2442005
Cardiac-specific disruption of the c-raf-1 gene induces cardiac dysfunction and apoptosis
O Yamaguchi, T Watanabe, K Nishida, K Kashiwase, Y Higuchi, T Takeda, ...
The Journal of clinical investigation 114 (7), 937-943, 2004
2422004
Combination of hypoglycemia and metformin impairs tumor metabolic plasticity and growth by modulating the PP2A-GSK3β-MCL-1 axis
M Elgendy, M Ciro, A Hosseini, J Weiszmann, L Mazzarella, E Ferrari, ...
Cancer cell 35 (5), 798-815. e5, 2019
2412019
Salmonella-Induced Caspase-2 Activation in Macrophages: A Novel Mechanism in Pathogen-Mediated Apoptosis
V Jesenberger, KJ Procyk, J Yuan, S Reipert, M Baccarini
The Journal of experimental medicine 192 (7), 1035-1046, 2000
2352000
Ras-dependent and-independent pathways target the mitogen-activated protein kinase network in macrophages
D Büscher, RA Hipskind, S Krautwald, T Reimann, M Baccarini
Molecular and cellular biology 15 (1), 466-475, 1995
2331995
A Mek1–Mek2 heterodimer determines the strength and duration of the Erk signal
F Catalanotti, G Reyes, V Jesenberger, G Galabova-Kovacs, ...
Nature structural & molecular biology 16 (3), 294-303, 2009
2172009
Growth Phase-Regulated Induction ofSalmonella-Induced Macrophage Apoptosis Correlates with Transient Expression of SPI-1 Genes
U Lundberg, U Vinatzer, D Berdnik, A von Gabain, M Baccarini
Journal of bacteriology 181 (11), 3433-3437, 1999
2161999
Lipopolysaccharide induces activation of the Raf-1/MAP kinase pathway. A putative role for Raf-1 in the induction of the IL-1 beta and the TNF-alpha genes.
T Reimann, D Büscher, RA Hipskind, S Krautwald, ML Lohmann-Matthes, ...
Journal of immunology (Baltimore, Md.: 1950) 153 (12), 5740-5749, 1994
1941994
Second nature: biological functions of the Raf-1 “kinase”
M Baccarini
FEBS letters 579 (15), 3271-3277, 2005
1902005
Targets of Raf in tumorigenesis
TS Niault, M Baccarini
Carcinogenesis 31 (7), 1165-1174, 2010
1812010
Fibronectin-tissue transglutaminase matrix rescues RGD-impaired cell adhesion through syndecan-4 and β1 integrin co-signaling
D Telci, Z Wang, X Li, EAM Verderio, MJ Humphries, M Baccarini, ...
Journal of biological chemistry 283 (30), 20937-20947, 2008
1702008
Transient activation of RAF-1, MEK, and ERK2 coincides kinetically with ternary complex factor phosphorylation and immediate-early gene promoter activity in vivo
RA Hipskind, M Baccarini, A Nordheim
Molecular and cellular biology, 1994
1661994
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Artikelen 1–20